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Generic Nolvadex - Tamoxifine
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CLASS and MECHANISM of Action
Generic "Nolvadex" is an oral selective estrogen receptor modulator which is used in breast cancer treatment, and is currently the world's largest selling breast cancer treatment. It is used for the treatment of early and advanced breast cancer in pre- and post-menopausal women. It is also approved by the Food and Drug Administration (FDA) for the reduction of the incidence of breast cancer in women at high risk of developing the disease. It has been further approved for the reduction of contralateral (in the opposite breast) breast cancer. Generic "Nolvadex" competes with oestrogen in the body for oestrogen receptors in breast tissue so that transcription of oestrogen-responsive genes is inhibited.
Active Ingredients: Tamoxifine citrate
Other Ingredients: lactose, cornstarch, gelatin, crosscarmelose, sodium, magnesium stearate, methylhydroxy, macrogol 300 and titanium dioxide.
What is Generic "Nolvadex"PRESCRIBED for?
Generic "Nolvadex", an anticancer drug, is given to treat breast cancer. It also has proved effective when cancer has spread to other parts of the body. Generic "Nolvadex" is most effective in stopping the kind of breast cancer that thrives on estrogen.
Generic "Nolvadex" is also prescribed to reduce the risk of invasive breast cancer following surgery and radiation therapy for ductal carcinoma in situ. The drug can also be used to reduce the odds of breast cancer in women at high risk of developing the disease. It does not completely eliminate your chances, but in a five-year study of over 1,500 high-risk women, it slashed the number of cases by 44 percent.
How should I take Generic "Nolvadex"?
Take Generic "Nolvadex" exactly as prescribed. Do not stop taking this medication without first consulting your doctor. It may be necessary to continue taking the drug for several years.
Generic Generic "Nolvadex"is usually prescribed as a single daily dose and this should be taken at the same time each day: the actual time does not matter. Some women prefer to take the tablet with food as it may make you feel sick and can leave a metallic taste in your mouth. It is best to find a convenient time and stick to it. Trials are under way to determine how long Generic "Nolvadex" should be taken for after surgery for breast cancer. It is commonly prescribed for five years, although some doctors prescribe it for two years and others indefinitely. Currently it is thought that five years of treatment is probably best.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
What are the CONTRADICTIONS for taking Generic "Nolvadex"?
Do not take Generic "Nolvadex" if you are sensitive to it or have ever had an allergic reaction to it.
If you are taking the blood-thinning drug Coumadin or have had problems with clots in your veins or your lungs, you should not take Generic "Nolvadex" to reduce the risk of breast cancer, and when taking it to treat an actual case of the disease, you should use it with caution.
Like most drugs, Generic "Nolvadex" should not be taken during pregnancy. Even though it can affect a woman's periods, Generic "Nolvadex" is not a contraceptive, so reliable contraception must be used. It is important to avoid pregnancy while taking Generic "Nolvadex", because the drug could harm the unborn child. Since Generic "Nolvadex" is an anti-estrogen drug, you will need to use a non-hormonal form of contraception, such as a condom and/or diaphragm, and not birth control pills. If you accidentally become pregnant while taking Generic "Nolvadex", or within 2 months after you have stopped taking it, discuss this with your doctor immediately.
Because Generic "Nolvadex" might cause serious harm to a nursing infant, you should not breastfeed your baby while taking this drug. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.
What Happens if I MISS A DOSE?
If you miss a dose of this medicine, do not take the missed dose at all and do not double the next one. Instead, go back to your regular dosing schedule and check with your doctor.
What Happens if I OVERDOSE?
An overdose of Generic Generic "Nolvadex"is unlikely to threaten life. Call an emergency room or a poison control center for advice if you suspect an overdose. Symptoms of a Generic "Nolvadex" overdose are unknown, but nausea, vomiting, seizures, tremor, or dizziness may be expected.
What are the possible SIDE EFFECTS of Generic "Nolvadex"?
Side effects from "Generic Nolvadex" are usually mild and rarely require the drug to be stopped. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Generic "Nolvadex".
More common side effects:
- hot flashes
Less common side effects:
- bone pain
- skin rash
- tumor pain
- menstrual irregularities
- vaginal bleeding
- vaginal discharge
Rare side effects:
- blood clots
- distaste for food
- hair thinning or partial loss
- liver disorders
- swelling of arms or legs
- vaginal itching or dryness
- visual problems.
What other drugs can INTERACT with Generic "Nolvadex"?
If Generic "Nolvadex" is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Generic "Nolvadex" with the following:
You may not be able to take Generic "Nolvadex" or you may require special monitoring or a dosage adjustment if you are taking any of the medicines listed above
- Blood-thinning drugs such as Coumadin
- Cancer drugs such as Cytoxan
- Rifampin (Rifadin)
Drugs other than those listed here may also interact with Generic "Nolvadex". Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.
Keep all appointments with your doctor. You will need to have gynecological examinations (examinations of the female organs) regularly to find early signs of cancer of the uterus. If you are thinking about taking Generic "Nolvadex" to reduce the chance that you will develop breast cancer, you should talk to your doctor about the risks and benefits of this treatment.